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Absence of amplification of the FGFR1-gene in human malignant mesothelioma of the pleura: a pilot study

BACKGROUND: Mesothelioma (MPM) is a rare malignant disease with a worse outcome. Fibroblast growth factor 1 (FGFR1) may be an interesting target for selective tyrosine kinases inhibitors (TKI) in MPM. The aim of this study was to evaluate the amplification of the FGFR1 gene in patients suffering fro...

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Detalles Bibliográficos
Autores principales: Plönes, Till, Beckers, Frank, Engel-Riedel, Walburga, Stoelben, Erich, Brockmann, Michael, Schildgen, Verena, Schildgen, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148949/
https://www.ncbi.nlm.nih.gov/pubmed/25138167
http://dx.doi.org/10.1186/1756-0500-7-549