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Role of CpG deserts in the epigenetic transgenerational inheritance of differential DNA methylation regions

BACKGROUND: Previously a variety of environmental toxicants were found to promote the epigenetic transgenerational inheritance of disease through differential DNA methylation regions (DMRs), termed epimutations, present in sperm. The transgenerational epimutations in sperm and somatic cells identifi...

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Detalles Bibliográficos
Autores principales: Skinner, Michael K, Guerrero-Bosagna, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149044/
https://www.ncbi.nlm.nih.gov/pubmed/25142051
http://dx.doi.org/10.1186/1471-2164-15-692