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Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window
BACKGROUND: Simian immunodeficiency virus (SIV) infection of nonhuman primates is the predominant model for preclinical evaluation of human immunodeficiency virus (HIV) vaccines. These studies frequently utilize high-doses of SIV that ensure infection after a single challenge but do not recapitulate...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149191/ https://www.ncbi.nlm.nih.gov/pubmed/25125288 http://dx.doi.org/10.1186/s12977-014-0066-z |