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Rapid, repeated, low-dose challenges with SIVmac239 infect animals in a condensed challenge window

BACKGROUND: Simian immunodeficiency virus (SIV) infection of nonhuman primates is the predominant model for preclinical evaluation of human immunodeficiency virus (HIV) vaccines. These studies frequently utilize high-doses of SIV that ensure infection after a single challenge but do not recapitulate...

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Detalles Bibliográficos
Autores principales:	Greene, Justin M, Weiler, Andrea M, Reynolds, Matthew R, Cain, Brian T, Pham, Ngoc H, Ericsen, Adam J, Peterson, Eric J, Crosno, Kristin, Brunner, Kevin, Friedrich, Thomas C, O’Connor, David H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149191/ https://www.ncbi.nlm.nih.gov/pubmed/25125288 http://dx.doi.org/10.1186/s12977-014-0066-z

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