Lithium ameliorates lipopolysaccharide-induced microglial activation via inhibition of toll-like receptor 4 expression by activating the PI3K/Akt/FoxO1 pathway

BACKGROUND: Lithium, an effective mood stabilizer for the treatment of bipolar disorders, has been recently suggested to have a role in neuroprotection during neurodegenerative diseases. The pathogenesis of neurological disorders often involves the activation of microglia and associated inflammatory...

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Detalles Bibliográficos
Autores principales: Dong, Hongquan, Zhang, Xiang, Dai, Xiaonan, Lu, Shunmei, Gui, Bo, Jin, Wenjie, Zhang, Susu, Zhang, Shu, Qian, Yanning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149204/
https://www.ncbi.nlm.nih.gov/pubmed/25115727
http://dx.doi.org/10.1186/s12974-014-0140-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149204/
https://www.ncbi.nlm.nih.gov/pubmed/25115727
http://dx.doi.org/10.1186/s12974-014-0140-4

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