Mutation and expression analysis in medulloblastoma yields prognostic variants and a putative mechanism of disease for i17q tumors

Current consensus identifies four molecular subtypes of medulloblastoma (MB): WNT, sonic hedgehog (SHH), and groups “3/C” and “4/D”. Group 4 is not well characterized, but harbors the most frequently observed chromosomal abnormality in MB, i17q, whose presence may confer a worse outcome. Recent publ...

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Detalles Bibliográficos
Autores principales: Bien-Willner, Gabriel A, Mitra, Robi D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149211/
https://www.ncbi.nlm.nih.gov/pubmed/25030029
http://dx.doi.org/10.1186/s40478-014-0074-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149211/
https://www.ncbi.nlm.nih.gov/pubmed/25030029
http://dx.doi.org/10.1186/s40478-014-0074-1

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