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A neuronal function of the tumor suppressor protein merlin

Mutagenic loss of the NF2 tumor suppressor gene encoded protein merlin is known to provoke the hereditary neoplasia syndrome, Neurofibromatosis type 2 (NF2). In addition to glial cell-derived tumors in the PNS and CNS, disease-related lesions also affect the skin and the eyes. Furthermore, 60% of NF...

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Detalles Bibliográficos
Autores principales: Schulz, Alexander, Zoch, Ansgar, Morrison, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149232/
https://www.ncbi.nlm.nih.gov/pubmed/25012216
http://dx.doi.org/10.1186/s40478-014-0082-1