Cargando…

Altered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer’s disease correlates with pathology

Synaptic dysfunction occurs early in the progression of Alzheimer’s disease (AD) and correlates with memory decline. There is emerging evidence that deregulation of Erythropoietin-producing hepatocellular (Eph) receptor tyrosine kinases (RTK) signaling contributes to the aberrant synaptic functions...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosenberger, Andrea FN, Rozemuller, Annemieke JM, van der Flier, Wiesje M, Scheltens, Philip, van der Vies, Saskia M, Hoozemans, Jeroen JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149234/
https://www.ncbi.nlm.nih.gov/pubmed/25027113
http://dx.doi.org/10.1186/s40478-014-0079-9