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Altered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer’s disease correlates with pathology
Synaptic dysfunction occurs early in the progression of Alzheimer’s disease (AD) and correlates with memory decline. There is emerging evidence that deregulation of Erythropoietin-producing hepatocellular (Eph) receptor tyrosine kinases (RTK) signaling contributes to the aberrant synaptic functions...
Autores principales: | Rosenberger, Andrea FN, Rozemuller, Annemieke JM, van der Flier, Wiesje M, Scheltens, Philip, van der Vies, Saskia M, Hoozemans, Jeroen JM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149234/ https://www.ncbi.nlm.nih.gov/pubmed/25027113 http://dx.doi.org/10.1186/s40478-014-0079-9 |
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