Genetic drivers of metastatic dissemination in sonic hedgehog medulloblastoma

Leptomeningeal dissemination (LMD), the metastatic spread of tumor cells via the cerebrospinal fluid to the brain and spinal cord, is an ominous prognostic sign for patients with the pediatric brain tumor medulloblastoma. The need to reduce the risk of LMD has driven the development of aggressive tr...

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Detalles Bibliográficos
Autores principales: Jenkins, Noah C, Kalra, Ricky R, Dubuc, Adrian, Sivakumar, Walavan, Pedone, Carolyn A, Wu, Xiaochong, Taylor, Michael D, Fults, Daniel W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149244/
https://www.ncbi.nlm.nih.gov/pubmed/25059231
http://dx.doi.org/10.1186/s40478-014-0085-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149244/
https://www.ncbi.nlm.nih.gov/pubmed/25059231
http://dx.doi.org/10.1186/s40478-014-0085-y

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