Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

BACKGROUND: Glucocorticoid receptor (GR) is a hormone-activated, DNA-binding transcriptional regulatory factor that controls inflammation, metabolism, stress responses, and other physiological processes. In vitro, GR binds as an inverted dimer to a motif consisting of two imperfectly palindromic 6 b...

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Detalles Bibliográficos
Autores principales: Schiller, Benjamin J, Chodankar, Rajas, Watson, Lisa C, Stallcup, Michael R, Yamamoto, Keith R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149261/
https://www.ncbi.nlm.nih.gov/pubmed/25085117
http://dx.doi.org/10.1186/s13059-014-0418-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149261/
https://www.ncbi.nlm.nih.gov/pubmed/25085117
http://dx.doi.org/10.1186/s13059-014-0418-y

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