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Influence of multiple APOE genetic variants on cognitive function in a cohort of older men – results from the Normative Aging Study
BACKGROUND: APOE is the biomarker with the greatest known influence on cognitive function; however, the effect of complex haplotypes involving polymorphisms rs449647, rs405509, rs440446, rs429358 and rs7412 has never been studied in older populations. METHODS: We evaluated APOE polymorphisms using m...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149270/ https://www.ncbi.nlm.nih.gov/pubmed/25085564 http://dx.doi.org/10.1186/s12888-014-0223-x |