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Etanercept restores normal insulin signal transduction in β2-adrenergic receptor knockout mice
BACKGROUND: Inhibition of TNFα protects the retina against diabetic-like changes in rodent models. The mechanism by which TNFα induces deleterious retinal changes is not known. Previously, we have shown that TNFα can inhibit normal insulin signal transduction, leading to increased apoptosis in both...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149274/ https://www.ncbi.nlm.nih.gov/pubmed/25138272 http://dx.doi.org/10.1186/s12974-014-0137-z |