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Etanercept restores normal insulin signal transduction in β2-adrenergic receptor knockout mice

BACKGROUND: Inhibition of TNFα protects the retina against diabetic-like changes in rodent models. The mechanism by which TNFα induces deleterious retinal changes is not known. Previously, we have shown that TNFα can inhibit normal insulin signal transduction, leading to increased apoptosis in both...

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Detalles Bibliográficos
Autores principales: Jiang, Youde, Zhang, Qiuhua, Ye, Eun-Ah, Steinle, Jena J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149274/
https://www.ncbi.nlm.nih.gov/pubmed/25138272
http://dx.doi.org/10.1186/s12974-014-0137-z