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Enteric Bacterial Metabolites Propionic and Butyric Acid Modulate Gene Expression, Including CREB-Dependent Catecholaminergic Neurotransmission, in PC12 Cells - Possible Relevance to Autism Spectrum Disorders

Alterations in gut microbiome composition have an emerging role in health and disease including brain function and behavior. Short chain fatty acids (SCFA) like propionic (PPA), and butyric acid (BA), which are present in diet and are fermentation products of many gastrointestinal bacteria, are show...

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Detalles Bibliográficos
Autores principales: Nankova, Bistra B., Agarwal, Raj, MacFabe, Derrick F., La Gamma, Edmund F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149359/
https://www.ncbi.nlm.nih.gov/pubmed/25170769
http://dx.doi.org/10.1371/journal.pone.0103740