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Potential of 2-Hydroxy-3-Phenylsulfanylmethyl-[1,4]-Naphthoquinones against Leishmania (L.) infantum: Biological Activity and Structure-Activity Relationships

Naphtoquinones have been used as promising scaffolds for drug design studies against protozoan parasites. Considering the highly toxic and limited therapeutic arsenal, the global negligence with tropical diseases and the elevated prevalence of co-morbidities especially in developing countries, the p...

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Detalles Bibliográficos
Autores principales: Pinto, Erika G., Santos, Isabela O., Schmidt, Thomas J., Borborema, Samanta E. T., Ferreira, Vitor F., Rocha, David R., Tempone, Andre G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149375/
https://www.ncbi.nlm.nih.gov/pubmed/25171058
http://dx.doi.org/10.1371/journal.pone.0105127