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Potential of 2-Hydroxy-3-Phenylsulfanylmethyl-[1,4]-Naphthoquinones against Leishmania (L.) infantum: Biological Activity and Structure-Activity Relationships
Naphtoquinones have been used as promising scaffolds for drug design studies against protozoan parasites. Considering the highly toxic and limited therapeutic arsenal, the global negligence with tropical diseases and the elevated prevalence of co-morbidities especially in developing countries, the p...
Autores principales: | Pinto, Erika G., Santos, Isabela O., Schmidt, Thomas J., Borborema, Samanta E. T., Ferreira, Vitor F., Rocha, David R., Tempone, Andre G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149375/ https://www.ncbi.nlm.nih.gov/pubmed/25171058 http://dx.doi.org/10.1371/journal.pone.0105127 |
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