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Update on the Use of l-Asparaginase in Infants and Adolescent Patients with Acute Lymphoblastic Leukemia

Great improvements have been made in acute lymphoblastic leukemia (ALL) treatment in the past decades, especially due to the use of l-asparaginase (l-ASP). Despite the significant success rate, several side effects mainly caused by toxicity, asparaginase silent inactivation, and cellular resistance,...

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Detalles Bibliográficos
Autores principales: Andrade, Augusto F, Borges, Kleiton S, Silveira, Vanessa S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149393/
https://www.ncbi.nlm.nih.gov/pubmed/25210485
http://dx.doi.org/10.4137/CMO.S10242