Expansion of Human and Murine Hematopoietic Stem and Progenitor Cells Ex Vivo without Genetic Modification Using MYC and Bcl-2 Fusion Proteins

The long-term repopulating hematopoietic stem cell (HSC) population can self-renew in vivo, support hematopoiesis for the lifetime of the individual, and is of critical importance in the context of bone marrow stem cell transplantation. The mechanisms that regulate the expansion of HSCs in vivo and...

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Detalles Bibliográficos
Autores principales: Bird, Gregory A., Polsky, Avital, Estes, Patricia, Hanlon, Teri, Hamilton, Haley, Morton, John J., Gutman, Jonathan, Jimeno, Antonio, Turner, Brian C., Refaeli, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149411/
https://www.ncbi.nlm.nih.gov/pubmed/25170611
http://dx.doi.org/10.1371/journal.pone.0105525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149411/
https://www.ncbi.nlm.nih.gov/pubmed/25170611
http://dx.doi.org/10.1371/journal.pone.0105525

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