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The FYVE Domain of Smad Anchor for Receptor Activation (SARA) Is Required to Prevent Skin Carcinogenesis, but Not in Mouse Development

Smad Anchor for Receptor Activation (SARA) has been reported as a critical role in TGF-β signal transduction by recruiting non-activated Smad2/3 to the TGF-β receptor and ensuring appropriate subcellular localization of the activated receptor-bound complex. However, controversies still exist in prev...

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Detalles Bibliográficos
Autores principales: Chang, Huang-Ming, Lin, Yu-Ying, Tsai, Pei-Chun, Liang, Chung-Tiang, Yan, Yu-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149420/
https://www.ncbi.nlm.nih.gov/pubmed/25170969
http://dx.doi.org/10.1371/journal.pone.0105299