Cargando…

Upregulation of ERK1/2-eNOS via AT2 Receptors Decreases the Contractile Response to Angiotensin II in Resistance Mesenteric Arteries from Obese Rats

It has been clearly established that mitogen-activated protein kinases (MAPKS) are important mediators of angiotensin II (Ang II) signaling via AT1 receptors in the vasculature. However, evidence for a role of these kinases in changes of Ang II-induced vasoconstriction in obesity is still lacking. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagihara, Graziela N., Lobato, Nubia S., Filgueira, Fernando P., Akamine, Eliana H., Aragão, Danielle S., Casarini, Dulce E., Carvalho, Maria Helena C., Fortes, Zuleica B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149482/
https://www.ncbi.nlm.nih.gov/pubmed/25170617
http://dx.doi.org/10.1371/journal.pone.0106029