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HIV-1 Vpr Induces Interferon-Stimulated Genes in Human Monocyte-Derived Macrophages

Macrophages act as reservoirs of human immunodeficiency virus type 1 (HIV-1) and play an important role in its transmission to other cells. HIV-1 Vpr is a multi-functional protein involved in HIV-1 replication and pathogenesis; however, its exact role in HIV-1-infected human macrophages remains poor...

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Detalles Bibliográficos
Autores principales: Zahoor, Muhammad Atif, Xue, Guangai, Sato, Hirotaka, Murakami, Tomoyuki, Takeshima, Shin-nosuke, Aida, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149569/
https://www.ncbi.nlm.nih.gov/pubmed/25170834
http://dx.doi.org/10.1371/journal.pone.0106418