miR-34a Blocks Osteoporosis and Bone Metastasis by Inhibiting Osteoclastogenesis and Tgif2

The bone resorbing osteoclasts significantly contribute to osteoporosis and cancer bone metastases(1-3). MicroRNAs (miRNAs) play important roles in physiology and disease(4,5), and present tremendous therapeutic potential(6). Nonetheless, how miRNAs regulate skeletal biology is underexplored. Here w...

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Detalles Bibliográficos
Autores principales: Krzeszinskia, Jing Y., Wei, Wei, Huynh, HoangDinh, Jin, Zixue, Wang, Xunde, Chang, Tsung-Cheng, Xie, Xian-Jin, He, Lin, Mangala, Lingegowda S., Lopez-Berestein, Gabriel, Sood, Anil K., Mendell, Joshua T., Wan, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149606/
https://www.ncbi.nlm.nih.gov/pubmed/25043055
http://dx.doi.org/10.1038/nature13375

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149606/
https://www.ncbi.nlm.nih.gov/pubmed/25043055
http://dx.doi.org/10.1038/nature13375

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