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miR-34a Blocks Osteoporosis and Bone Metastasis by Inhibiting Osteoclastogenesis and Tgif2
The bone resorbing osteoclasts significantly contribute to osteoporosis and cancer bone metastases(1-3). MicroRNAs (miRNAs) play important roles in physiology and disease(4,5), and present tremendous therapeutic potential(6). Nonetheless, how miRNAs regulate skeletal biology is underexplored. Here w...
Autores principales: | Krzeszinskia, Jing Y., Wei, Wei, Huynh, HoangDinh, Jin, Zixue, Wang, Xunde, Chang, Tsung-Cheng, Xie, Xian-Jin, He, Lin, Mangala, Lingegowda S., Lopez-Berestein, Gabriel, Sood, Anil K., Mendell, Joshua T., Wan, Yihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149606/ https://www.ncbi.nlm.nih.gov/pubmed/25043055 http://dx.doi.org/10.1038/nature13375 |
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