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116 Strategies and mechanisms for vaccine induction of mucosal T cell immunity

Most HIV transmission is through mucosal surfaces. We previously found in mice that CD8 T cells must be in the local mucosa to prevent mucosal viral transmission. Intrarectal delivery was most effective, but not so practical. We devised a strategy to mimic intrarectal delivery through the oral route...

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Detalles Bibliográficos
Autor principal: Berzofsky, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149612/
http://dx.doi.org/10.1097/01.qai.0000446696.61718.ff