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128 Cure of HBV infection: can APOBEC3 deaminases mediate it?
Current antivirals cannot efficiently control but not eliminate hepatitis B virus (HBV) in the 300 million carriers at risk to develop liver diseases and cancer, because HBV establishes a stable nuclear cccDNA in infected hepatocytes. Interferon can clear HBV but therapeutic dosing is limited by sid...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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JAIDS Journal of Acquired Immune Deficiency Syndromes
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149614/ http://dx.doi.org/10.1097/01.qai.0000446708.47107.00 |