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133 Structural basis for ebolavirus matrix assembly and budding; protein plasticity allows multiple functions
Proteins, particularly viral proteins, can be multifunctional, but the mechanism(s) behind this trait are not fully understood. Here, we illustrate through multiple crystal structures, biochemistry and cellular microscopy that the Ebola virus VP40 protein rearranges into different structures, each w...
Autores principales: | Bornholdt, Zachary, Noda, Takeshi, Abelson, Dafna, Halfmann, Peter, Wood, Malcolm, Kawaoa, Yoshihiro, Saphire, Erica Ollmann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JAIDS Journal of Acquired Immune Deficiency Syndromes
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149652/ http://dx.doi.org/10.1097/01.qai.0000446713.32982.25 |
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