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118 The dense glycan shield on the HIV envelope: the Achilles heel of the virus?
The envelope gp120 of HIV contains an unusual high amount of N-glycans that serves as a dense shield to hide immunogenic epitopes on gp120 against the immune system. There exists a wide variety of glycan-binding agents with different specificities to recognize carbohydrate moieties present on the HI...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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JAIDS Journal of Acquired Immune Deficiency Syndromes
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149660/ http://dx.doi.org/10.1097/01.qai.0000446698.38847.fd |