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118 The dense glycan shield on the HIV envelope: the Achilles heel of the virus?

The envelope gp120 of HIV contains an unusual high amount of N-glycans that serves as a dense shield to hide immunogenic epitopes on gp120 against the immune system. There exists a wide variety of glycan-binding agents with different specificities to recognize carbohydrate moieties present on the HI...

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Detalles Bibliográficos
Autor principal: Balzarini, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149660/
http://dx.doi.org/10.1097/01.qai.0000446698.38847.fd