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136 HIV-1 Nef regulates activity of endoplasmic reticulum chaperone calnexin
HIV-1 Nef promotes viral replication by downmodulating a number of cell surface transmembrane proteins, such as CD4, MHC-I and MHC-II, which are targeted by Nef to various degradation pathways. Nef is also responsible for downregulation of cellular cholesterol transporter ABCA1, and this effect cont...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
JAIDS Journal of Acquired Immune Deficiency Syndromes
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149662/ http://dx.doi.org/10.1097/01.qai.0000446716.85972.b0 |