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Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling

BACKGROUND: Within the nucleus of eukaryotic cells, chromatin is organized into compact, silent regions called heterochromatin and more loosely packaged regions of euchromatin where transcription is more active. Although the existence of heterochromatin has been known for many years, the cellular fa...

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Detalles Bibliográficos
Autores principales: Xu, Na, Emelyanov, Alexander V, Fyodorov, Dmitry V, Skoultchi, Arthur I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149798/
https://www.ncbi.nlm.nih.gov/pubmed/25177369
http://dx.doi.org/10.1186/1756-8935-7-16