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Mice with an absent stress response are protected against ischemic renal injury

Inducible heat shock proteins (HSP), regulated by heat shock factor-1 (HSF-1), protect against renal cell injury in vitro. To determine whether HSPs ameliorate ischemic renal injury in vivo, HSF-1functional knock-out mice (HSF-KO) were compared with wild-type mice following bilateral ischemic renal...

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Detalles Bibliográficos
Autores principales: Sreedharan, Rajasree, Chen, Shaoying, Miller, Melody, Haribhai, Dipica, Williams, Calvin, Van Why, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149847/
https://www.ncbi.nlm.nih.gov/pubmed/24805105
http://dx.doi.org/10.1038/ki.2014.73