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Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli

A key role for podocytes in the pathogenesis of proteinuric renal diseases has been established. Angiotensin II causes depolarization and increased intracellular calcium concentration in podocytes; members of the cation TRPC channels family, particularly TRPC6, are proposed as proteins responsible f...

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Detalles Bibliográficos
Autores principales: Ilatovskaya, Daria V., Palygin, Oleg, Chubinskiy-Nadezhdin, Vladislav, Negulyaev, Yuri A., Ma, Rong, Birnbaumer, Lutz, Staruschenko, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149864/
https://www.ncbi.nlm.nih.gov/pubmed/24646854
http://dx.doi.org/10.1038/ki.2014.71