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Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
A key role for podocytes in the pathogenesis of proteinuric renal diseases has been established. Angiotensin II causes depolarization and increased intracellular calcium concentration in podocytes; members of the cation TRPC channels family, particularly TRPC6, are proposed as proteins responsible f...
Autores principales: | Ilatovskaya, Daria V., Palygin, Oleg, Chubinskiy-Nadezhdin, Vladislav, Negulyaev, Yuri A., Ma, Rong, Birnbaumer, Lutz, Staruschenko, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149864/ https://www.ncbi.nlm.nih.gov/pubmed/24646854 http://dx.doi.org/10.1038/ki.2014.71 |
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