Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation, and polypharmacological strategies

Developing pharmacological strategies for controlling ionizing radiation (IR)-induced cell death is important for both mitigating radiation damage and alleviating the side effects of anti-cancer radiotherapy manifested in surrounding tissue morbidity. Exposure to IR often triggers the onset of p53-d...

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Detalles Bibliográficos
Autores principales: Liu, Bing, Bhatt, Divesh, Oltvai, Zoltán N., Greenberger, Joel S., Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150106/
https://www.ncbi.nlm.nih.gov/pubmed/25175563
http://dx.doi.org/10.1038/srep06245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150106/
https://www.ncbi.nlm.nih.gov/pubmed/25175563
http://dx.doi.org/10.1038/srep06245

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