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MiR-424-5p reversed epithelial-mesenchymal transition of anchorage-independent HCC cells by directly targeting ICAT and suppressed HCC progression

Resistance to anoikis and Epithelial-mesenchymal transition (EMT) are two processes critically involved in cancer metastasis. In this study, we demonstrated that after anchorage deprival, hepatocellular carcinoma (HCC) cells not only resisted anoikis, but also exhibited EMT process. Microarray expre...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, Li, Tao, Guo, Pengbo, Kang, Jia, Wei, Qing, Jia, Xiaoqing, Zhao, Wei, Huai, Wanwan, Qiu, Yumin, Sun, Lei, Han, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150107/
https://www.ncbi.nlm.nih.gov/pubmed/25175916
http://dx.doi.org/10.1038/srep06248