GH Dysfunction in Engrailed-2 Knockout Mice, a Model for Autism Spectrum Disorders

Insulin-like growth factor 1 (IGF-1) signaling promotes brain development and plasticity. Altered IGF-1 expression has been associated to autism spectrum disorders (ASD). IGF-1 levels were found increased in the blood and decreased in the cerebrospinal fluid of ASD children. Accordingly, IGF-1 treat...

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Detalles Bibliográficos
Autores principales: Provenzano, Giovanni, Clementi, Elena, Genovesi, Sacha, Scali, Manuela, Tripathi, Prem Prakash, Sgadò, Paola, Bozzi, Yuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150208/
https://www.ncbi.nlm.nih.gov/pubmed/25225635
http://dx.doi.org/10.3389/fped.2014.00092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150208/
https://www.ncbi.nlm.nih.gov/pubmed/25225635
http://dx.doi.org/10.3389/fped.2014.00092

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