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ERBB3 is required for metastasis formation of melanoma cells

Melanoma is curable when it is at an early phase but is lethal once it becomes metastatic. The recent development of BRAF(V600E) inhibitors (BIs) showed great promise in treating metastatic melanoma, but resistance developed quickly in the treated patients, and these inhibitors are not effective on...

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Detalles Bibliográficos
Autores principales: Tiwary, S, Preziosi, M, Rothberg, P G, Zeitouni, N, Corson, N, Xu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150209/
https://www.ncbi.nlm.nih.gov/pubmed/25000258
http://dx.doi.org/10.1038/oncsis.2014.23