MUC1 regulates cyclin D1 gene expression through p120 catenin and β-catenin

MUC1 interacts with β-catenin and p120 catenin to modulate WNT signaling. We investigated the effect of overexpressing MUC1 on the regulation of cyclin D1, a downstream target for the WNT/β-catenin signaling pathway, in two human pancreatic cancer cell lines, Panc-1 and S2-013. We observed a signifi...

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Detalles Bibliográficos
Autores principales: Liu, X, Caffrey, T C, Steele, M M, Mohr, A, Singh, P K, Radhakrishnan, P, Kelly, D L, Wen, Y, Hollingsworth, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150213/
https://www.ncbi.nlm.nih.gov/pubmed/24979278
http://dx.doi.org/10.1038/oncsis.2014.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150213/
https://www.ncbi.nlm.nih.gov/pubmed/24979278
http://dx.doi.org/10.1038/oncsis.2014.19

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