Oncogenic fusion proteins expressed in immature hematopoietic cells fail to recapitulate the transcriptional changes observed in human AML

Reciprocal chromosomal translocations are observed in one-third of acute myeloid leukemia (AML) cases. Targeting and understanding the effects of the resulting aberrant oncogenic fusion proteins may help developing drugs against specific leukemic subtypes, as demonstrated earlier by the use of ATRA...

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Detalles Bibliográficos
Autores principales: Rapin, N, Porse, B T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150216/
https://www.ncbi.nlm.nih.gov/pubmed/24932908
http://dx.doi.org/10.1038/oncsis.2014.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150216/
https://www.ncbi.nlm.nih.gov/pubmed/24932908
http://dx.doi.org/10.1038/oncsis.2014.22

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