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Label-free, live optical imaging of reprogrammed bipolar disorder patient-derived cells reveals a functional correlate of lithium responsiveness

Development of novel treatments and diagnostic tools for psychiatric illness has been hindered by the absence of cellular models of disease. With the advent of cellular reprogramming, it may be possible to recapitulate the disease biology of psychiatric disorders using patient skin cells transdiffer...

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Detalles Bibliográficos
Autores principales: Wang, J L, Shamah, S M, Sun, A X, Waldman, I D, Haggarty, S J, Perlis, R H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150245/
https://www.ncbi.nlm.nih.gov/pubmed/25158003
http://dx.doi.org/10.1038/tp.2014.72