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Oncogenic KRAS signalling in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is almost universally fatal. The annual number of deaths equals the number of newly diagnosed cases, despite maximal treatment. The overall 5-year survival rate of <5% has remained stubbornly unchanged over the last 30 years, despite tremendous efforts in p...

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Detalles Bibliográficos
Autores principales: Eser, S, Schnieke, A, Schneider, G, Saur, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150259/
https://www.ncbi.nlm.nih.gov/pubmed/24755884
http://dx.doi.org/10.1038/bjc.2014.215