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EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205

BACKGROUND: Expression of epithelial cell adhesion molecule (EpCAM) is deregulated in epithelial malignancies. Beside its role in cell adhesion, EpCAM acts as signalling molecule with tumour-promoting functions. Thus, EpCAM is part of the molecular network of oncogenic receptors and considered an in...

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Detalles Bibliográficos
Autores principales: Massoner, P, Thomm, T, Mack, B, Untergasser, G, Martowicz, A, Bobowski, K, Klocker, H, Gires, O, Puhr, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150273/
https://www.ncbi.nlm.nih.gov/pubmed/24992580
http://dx.doi.org/10.1038/bjc.2014.366