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Functional identity of receptors for proteolysis-inducing factor on human and murine skeletal muscle
BACKGROUND: Cachexia in both mice and humans is associated with tumour production of a sulphated glycoprotein called proteolysis-inducing factor (PIF). In mice PIF binds with high affinity to a surface receptor in skeletal muscle, but little is known about the human receptor. This study compares the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150279/ https://www.ncbi.nlm.nih.gov/pubmed/25101564 http://dx.doi.org/10.1038/bjc.2014.379 |