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Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase

In mammals, a family of TET enzymes producing oxidized forms of 5-methylcytosine (5mC) plays an important role in modulating DNA demethylation dynamics. In contrast, nothing is known about the function of a single TET orthologue present in invertebrates. Here, we show that the honeybee TET (AmTET) c...

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Detalles Bibliográficos
Autores principales: Wojciechowski, Marek, Rafalski, Dominik, Kucharski, Robert, Misztal, Katarzyna, Maleszka, Joanna, Bochtler, Matthias, Maleszka, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150289/
https://www.ncbi.nlm.nih.gov/pubmed/25100549
http://dx.doi.org/10.1098/rsob.140110