The CCA-end of P-tRNA Contacts Both the Human RPL36AL and the A-site Bound Translation Termination Factor eRF1 at the Peptidyl Transferase Center of the Human 80S Ribosome

We have demonstrated previously that the E-site specific protein RPL36AL present in human ribosomes can be crosslinked with the CCA-end of a P-tRNA in situ. Here we report the following: (i) We modeled RPL36AL into the structure of the archaeal ortholog RPL44E extracted from the known X-ray structur...

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Detalles Bibliográficos
Autores principales: Hountondji, Codjo, Bulygin, Konstantin, Créchet, Jean-Bernard, Woisard, Anne, Tuffery, Pierre, Nakayama, Jun-ichi, Frolova, Ludmila, Nierhaus, Knud H, Karpova, Galina, Baouz, Soria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150381/
https://www.ncbi.nlm.nih.gov/pubmed/25191528
http://dx.doi.org/10.2174/1874091X01408010052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150381/
https://www.ncbi.nlm.nih.gov/pubmed/25191528
http://dx.doi.org/10.2174/1874091X01408010052

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