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The CCA-end of P-tRNA Contacts Both the Human RPL36AL and the A-site Bound Translation Termination Factor eRF1 at the Peptidyl Transferase Center of the Human 80S Ribosome
We have demonstrated previously that the E-site specific protein RPL36AL present in human ribosomes can be crosslinked with the CCA-end of a P-tRNA in situ. Here we report the following: (i) We modeled RPL36AL into the structure of the archaeal ortholog RPL44E extracted from the known X-ray structur...
Autores principales: | Hountondji, Codjo, Bulygin, Konstantin, Créchet, Jean-Bernard, Woisard, Anne, Tuffery, Pierre, Nakayama, Jun-ichi, Frolova, Ludmila, Nierhaus, Knud H, Karpova, Galina, Baouz, Soria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150381/ https://www.ncbi.nlm.nih.gov/pubmed/25191528 http://dx.doi.org/10.2174/1874091X01408010052 |
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