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Predictors of Response to 24-Week Telaprevir-Based Triple Therapy for Treatment-Naïve Genotype 1b Chronic Hepatitis C Patients

We evaluated the genetic variation in rs8099917, substitutions in core amino acid (aa) 70, and the number of aa substitutions in the interferon sensitivity-determining region (ISDR) on the prediction of sustained virological response (SVR) in treatment-naïve hepatitis C virus (HCV) genotype 1b (G1b)...

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Detalles Bibliográficos
Autores principales: Abe, Hiroshi, Tsubota, Akihito, Shimada, Noritomo, Atsukawa, Masanori, Kato, Keizo, Takaguchi, Koichi, Asano, Toru, Chuganji, Yoshimichi, Sakamoto, Choitsu, Toyoda, Hidenori, Kumada, Takashi, Ide, Tatsuya, Sata, Michio, Aizawa, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150495/
https://www.ncbi.nlm.nih.gov/pubmed/25197269
http://dx.doi.org/10.1155/2014/549709