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Peripheral Blood WT1 Expression Predicts Relapse in AML Patients Undergoing Allogeneic Stem Cell Transplantation

To evaluate if WT1 expression may predict relapse after allo-SCT, we analyzed WT1 levels on peripheral blood (PB) and bone marrow (BM) before and after allo-SCT in 24 AML patients with WT1 overexpression at diagnosis. Five copies of WT1/ABL × 10(4) from PB were identified as the threshold value that...

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Detalles Bibliográficos
Autores principales: Malagola, Michele, Skert, Cristina, Ruggeri, Giuseppina, Turra, Alessandro, Ribolla, Rossella, Cancelli, Valeria, Cattina, Federica, Alghisi, Elisa, Bernardi, Simona, Perucca, Simone, Di Palma, Andrea, Borlenghi, Erika, Pagani, Chiara, Rossi, Giuseppe, Caimi, Luigi, Russo, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150519/
https://www.ncbi.nlm.nih.gov/pubmed/25202702
http://dx.doi.org/10.1155/2014/123079