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Imputation Without Doing Imputation: A New Method for the Detection of Non-Genotyped Causal Variants
Genome-wide association studies allow detection of non-genotyped disease-causing variants through testing of nearby genotyped SNPs. This approach may fail when there are no genotyped SNPs in strong LD with the causal variant. Several genotyped SNPs in weak LD with the causal variant may, however, co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150535/ https://www.ncbi.nlm.nih.gov/pubmed/24535679 http://dx.doi.org/10.1002/gepi.21792 |