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The Retinoblastoma Tumor Suppressor Pathway Modulates the Invasiveness of ErbB2 Positive Breast Cancer

The processes that control the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer remain poorly understood. Epidermal growth factor receptor 2 (ErbB2) over expression is common in DCIS, as is disruption of the retinoblastoma tumor suppressor (RB) pathway. Here we examined the c...

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Detalles Bibliográficos
Autores principales: Witkiewicz, Agnieszka K., Cox, Derek W., Rivadeneira, Dayana, Ertel, Adam E., Fortina, Paolo, Schwartz, Gordon F., Knudsen, Erik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150690/
https://www.ncbi.nlm.nih.gov/pubmed/24121271
http://dx.doi.org/10.1038/onc.2013.367