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Exquisite allele discrimination by toehold hairpin primers

The ability to detect and monitor single nucleotide polymorphisms (SNPs) in biological samples is an enabling research and clinical tool. We have developed a surprising, inexpensive primer design method that provides exquisite discrimination between SNPs. The field of DNA computation is largely reli...

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Detalles Bibliográficos
Autores principales: Byrom, Michelle, Bhadra, Sanchita, Jiang, Yu Sherry, Ellington, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150758/
https://www.ncbi.nlm.nih.gov/pubmed/24990378
http://dx.doi.org/10.1093/nar/gku558